2-Chloro-3-methylbenzoic Acid CAS 15068-35-6

Product name:2-Chloro-3-methylbenzoic acid
CAS:15068-35-6
MF:C8H7ClO2
MW:170.59

Melting point: 142-144°C
Boiling point: 288.7±20.0 °C
Density: 1.310±0.06 g/cm3

Purity:≥99%

White crystalline powder

1. 2-Chloro-3-methylbenzoic acid CAS 15068-35-6 is used as a key intermediate in pharmaceutical development, particularly for the synthesis of anti-inflammatory and analgesic drugs.
2. 2-Chloro-3-methylbenzoic acid CAS 15068-35-6 serves as a building block for agrochemicals, including herbicides, and for specialty polymers to enhance thermal stability and chemical resistance .
3. 2-Chloro-3-methylbenzoic acid CAS 15068-35-6 is employed in nucleophilic aromatic substitution reactions for ether and amine formation, and in amide bond formation via coupling reagents like HATU or EDC/HOBt .
4. 2-Chloro-3-methylbenzoic acid CAS 15068-35-6 is utilized as a substrate for palladium-catalyzed cross-coupling reactions (Suzuki, Heck, Buchwald-Hartwig) and as a Grignard reagent precursor .

1. Store 2-Chloro-3-methylbenzoic acid CAS 15068-35-6 at room temperature, preferably in a cool and dark place below 15°C .
2. 2-Chloro-3-methylbenzoic acid CAS 15068-35-6 should be kept in a tightly sealed container in a dry, well-ventilated area .
3. 2-Chloro-3-methylbenzoic acid CAS 15068-35-6 is classified as Storage Class 11 (Combustible Solids) .
4. For stock solutions, store 2-Chloro-3-methylbenzoic acid CAS 15068-35-6 at -80°C for up to 6 months or at -20°C for up to 1 month, avoiding repeated freeze-thaw cycles .

1. 2-Chloro-3-methylbenzoic acid CAS 15068-35-6 is harmful if swallowed (H302) .
2. 2-Chloro-3-methylbenzoic acid CAS 15068-35-6 causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335) according to some classifications .
3. 2-Chloro-3-methylbenzoic acid CAS 15068-35-6 may cause serious eye damage (H318) according to other supplier classifications .
4. The harmonized classification across suppliers varies, with some listing only H302 and others listing H315/H319/H335 or H302/H318 .

1. 2-Chloro-3-methylbenzoic acid CAS 15068-35-6 is not safe for ingestion and is classified as a warning-level hazard with the signal word Warning by most suppliers .
2. 2-Chloro-3-methylbenzoic acid CAS 15068-35-6 requires protective equipment including gloves, eye/face protection, and appropriate clothing, and hands should be washed thoroughly after handling .
3. 2-Chloro-3-methylbenzoic acid CAS 15068-35-6 should be used only in a well-ventilated area, avoiding dust formation and breathing dust .
4. 2-Chloro-3-methylbenzoic acid CAS 15068-35-6 must not be released into drains or the environment; dispose of contents and container to an approved waste disposal plant .

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