3-Hydroxy-2-Methylbenzoic Acid CAS 603-80-5

Product name:3-Hydroxy-2-Methylbenzoic acid
CAS:603-80-5
MF:C8H8O3
MW:152.15

EINECS: 629-955-7
Melting point: 143-148°C
Boiling point: 336.6±30.0 °C
Density: 1.304±0.06 g/cm3

Purity:≥99%

Yellow powder

1. 3-Hydroxy-2-methylbenzoic acid CAS 603-80-5 is used as a key building block in medicinal chemistry, most notably as the P2 ligand in HIV protease inhibitors such as nelfinavir.
2. 3-Hydroxy-2-methylbenzoic acid CAS 603-80-5 serves as a validated reference standard for nelfinavir mesylate Impurity A in pharmaceutical quality control, with a published MEKC method for its separation and quantification .
3. 3-Hydroxy-2-methylbenzoic acid CAS 603-80-5 is employed as an organic synthesis intermediate for pharmaceuticals, dyes, and functional materials .

1. Store 3-Hydroxy-2-methylbenzoic acid CAS 603-80-5 in a tightly closed container in a dry, cool, and well-ventilated place .
2. 3-Hydroxy-2-methylbenzoic acid CAS 603-80-5 is recommended for storage at room temperature in a cool and dark place below 15°C .
3. Keep 3-Hydroxy-2-methylbenzoic acid CAS 603-80-5 away from incompatible materials and foodstuff containers .

1. 3-Hydroxy-2-methylbenzoic acid CAS 603-80-5 causes skin irritation (H315) .
2. 3-Hydroxy-2-methylbenzoic acid CAS 603-80-5 causes serious eye irritation (H319) .
3. 3-Hydroxy-2-methylbenzoic acid CAS 603-80-5 may cause respiratory irritation (H335) according to some supplier classifications .
4. 3-Hydroxy-2-methylbenzoic acid CAS 603-80-5 has an NFPA health rating of 2, indicating intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury .

1. 3-Hydroxy-2-methylbenzoic acid CAS 603-80-5 is classified as a warning-level hazard (GHS07) with the signal word Warning under GHS .
2. 3-Hydroxy-2-methylbenzoic acid CAS 603-80-5 requires protective equipment including safety goggles with side-shields, protective gloves, and appropriate clothing, and hands should be washed thoroughly after handling .
3. 3-Hydroxy-2-methylbenzoic acid CAS 603-80-5 should be handled in a well-ventilated area, avoiding dust formation and contact with skin and eyes .
4. 3-Hydroxy-2-methylbenzoic acid CAS 603-80-5 must not be released into drains or the environment; spills should be collected in suitable closed containers for disposal according to local regulations .

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