4-Biphenylacetonitrile CAS 31603-77-7

Product name:4-Biphenylacetonitrile
CAS:31603-77-7
MF:C14H11N
MW:193.24

EINECS: 622-759-2
Melting point: 88-92 °C
Boiling point: 146-150°C
Density: 1.068±0.06 g/cm3

Purity:≥99%

Grayish pink solid

1. 4-Biphenylacetonitrile CAS 31603-77-7 is a useful synthetic intermediate used to study the adsorption orientation of biphenyl derivatives on gold colloidal surfaces with α-cyclodextrins.
2. 4-Biphenylacetonitrile CAS 31603-77-7 undergoes condensation with ethyl phenylpropiolate to yield biphenyl derivatives of acetylenic β-ketocyanide .
3. 4-Biphenylacetonitrile CAS 31603-77-7 is a key precursor for the biphenyl tetrazole pharmacophore found in angiotensin II receptor blockers such as Losartan and Irbesartan, and is also used in liquid crystal materials and organic electroluminescent devices .

1. Store 4-Biphenylacetonitrile CAS 31603-77-7 in a cool place with the container tightly closed in a dry and well-ventilated area .
2. 4-Biphenylacetonitrile CAS 31603-77-7 is recommended for storage at room temperature in a cool and dark place below 15°C .
3. Keep 4-Biphenylacetonitrile CAS 31603-77-7 away from strong oxidizing agents .

1. 4-Biphenylacetonitrile CAS 31603-77-7 is harmful if swallowed, in contact with skin, or if inhaled (H302+H312+H332) .
2. 4-Biphenylacetonitrile CAS 31603-77-7 causes skin irritation (H315) and serious eye irritation (H319) .
3. 4-Biphenylacetonitrile CAS 31603-77-7 may cause respiratory irritation (H335) .
4. 4-Biphenylacetonitrile CAS 31603-77-7 is classified as WGK 3 (severely hazardous to water) .

1. 4-Biphenylacetonitrile CAS 31603-77-7 is classified as a warning-level hazard (GHS07) with the signal word Warning under GHS .
2. 4-Biphenylacetonitrile CAS 31603-77-7 requires protective equipment including dust mask (N95 type), safety goggles, and gloves .
3. 4-Biphenylacetonitrile CAS 31603-77-7 should be used only outdoors or in a well-ventilated area, and skin should be washed thoroughly after handling .
4. 4-Biphenylacetonitrile CAS 31603-77-7 must not be released into drains or the environment; dispose of contents and container to an approved waste disposal plant .

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