N-Methylacetamide CAS 79-16-3

Product name:N-Methylacetamide
CAS:79-16-3
MF:C3H7NO
MW:73.09

EINECS: 201-182-6
Melting point: 26-28 °C
Boiling point: 204-206 °C
Density: 0.957 g/cm3

Purity:≥99%

White crystalline powder

1. N-Methylacetamide CAS 79-16-3 is used as a solvent in organic synthesis, particularly in the pharmaceutical industry for producing cephalosporins, and as an intermediate for pesticides and medicines.
2. N-Methylacetamide CAS 79-16-3 serves as a ligand to synthesize zirconium(IV) complexes and is used in the preparation of N-methyl-N-(3-thienyl)acetamide via copper-catalyzed coupling .
3. N-Methylacetamide CAS 79-16-3 functions as a minimal molecular model of the peptide bond for studying hydrogen-bonding networks, protein folding thermodynamics, and amide reactivity in biochemical research .

1. Store N-Methylacetamide CAS 79-16-3 at room temperature, preferably in a cool and dark place below 15°C, in a tightly closed container .
2. N-Methylacetamide CAS 79-16-3 is a solid with a melting point of 26-30°C and should be kept away from strong oxidizing agents to prevent hazardous decomposition .
3. For long-term storage of stock solutions, store N-Methylacetamide CAS 79-16-3 at -80°C for up to 2 years or at -20°C for up to 1 year .
 

1. N-Methylacetamide CAS 79-16-3 is classified as Reproductive Toxicity Category 1B (H360D, "May damage the unborn child") under the EU CLP Regulation and is listed as a Substance of Very High Concern .
2. N-Methylacetamide CAS 79-16-3 has low acute oral toxicity (LD50 = 5,000 mg/kg in rats) and is not classified for acute toxicity by the oral route .
3. N-Methylacetamide CAS 79-16-3 has limited data for skin and eye irritation, with classification not possible due to insufficient evidence .

1. N-Methylacetamide CAS 79-16-3 is not safe for uncontrolled handling due to its harmonized Repr. 1B classification and must be handled only by trained personnel .
2. N-Methylacetamide CAS 79-16-3 requires protective equipment including protective gloves, protective clothing, and eye/face protection (P280), and exposure or concern of exposure requires medical attention (P308+P313) .
3. N-Methylacetamide CAS 79-16-3 must be stored locked up (P405) and disposed of via approved waste disposal services (P501) .

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