Phenacetin CAS 62-44-2

Product name:Phenacetin
CAS:62-44-2
MF:C10H13NO2
MW:179.22
Density:1.245 g/cm3
Melting point:133-136°C

Purity:≥99%

White crystalline powder

Sulphated ash: ≤0.1%

Heavy metals: ≤0.001%

Pd: ≤1ppm

Loss on drying: ≤0.5%

Bacterial count: ≤80cfu/g

Yeasts & Molds: ≤80cfu/g

E.Coli: Not detected

1. Phenacetin CAS 62-44-2 was historically used as an analgesic and fever-reducing drug in both human and veterinary medicine before being withdrawn from the market.

2. Phenacetin CAS 62-44-2 has been used as a stabilizer for hydrogen peroxide in hair-bleaching and hair dye preparations.

3. Phenacetin CAS 62-44-2 is currently used as a laboratory reagent, particularly as a preferred marker for detecting CYP1A2-based inhibition potential in vitro.

4. Phenacetin CAS 62-44-2 has been used in homeopathic medicines and remains listed in some natural health product databases.

1. Store Phenacetin CAS 62-44-2 at room temperature in a cool, dark place below 15°C.

2. Phenacetin CAS 62-44-2 powder can be stored at -20°C for up to 3 years or at 4°C for up to 2 years.

3. Phenacetin CAS 62-44-2 stock solutions should be stored at -80°C for up to 2 years or at -20°C for up to 1 year.

4. Store Phenacetin CAS 62-44-2 away from incompatible materials and keep containers tightly closed in a dry, well-ventilated area.

1. Phenacetin CAS 62-44-2 is classified as a Group 1 human carcinogen by IARC, based on sufficient evidence of carcinogenicity in humans and experimental animals.

2. Phenacetin CAS 62-44-2 is harmful if swallowed (H302) and may cause kidney, liver, and blood disorders including methemoglobinemia.

3. Phenacetin CAS 62-44-2 is classified as a Category 2 germ cell mutagen (H341) and is reasonably anticipated to be a human carcinogen.

4. Phenacetin CAS 62-44-2 may cause cyanosis, dizziness, and respiratory depression upon human ingestion.

1. Phenacetin CAS 62-44-2 was withdrawn from the U.S. market in 1983 due to unacceptable levels of interstitial nephritis and potential carcinogenicity risks.

2. Phenacetin CAS 62-44-2 is not considered harmful to human health at current levels of exposure according to a Canadian government screening assessment, but it is recognized as having a health effect of concern due to its carcinogenic potential.

3. Phenacetin CAS 62-44-2 should be handled only by trained personnel with appropriate personal protective equipment in a well-ventilated area, due to its carcinogenic and mutagenic properties.

4. The use of Phenacetin CAS 62-44-2 in consumer products is restricted in many jurisdictions, and significant new activities involving this substance require regulatory notification and assessment.

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