Triphenylphosphine Oxide /TPPO CAS 791-28-6

Product name:Triphenylphosphine oxide /TPPO

CAS:791-28-6

MF:C18H15OP

MW:278.28

EINECS:212-338-8

Density:1.212 g/cm3

Melting point:154-158°C

Boiling point:360°C

Purity:≥99%

White crystalline powder

1. Triphenylphosphine oxide CAS 791-28-6 is used as a catalyst, Lewis base, and ligand for metals, and as a starting material for preparing other phosphorus compounds.
2. TPPO CAS 791-28-6 is employed in epoxidations, Michael reactions, and coupling reactions, and reacts with copper(II) halides to form coordination complexes .
3. Triphenylphosphine oxide CAS 791-28-6 acts as a crystallization aid for chemical compounds and is used for extraction, separation, and spectrophotometric determination of cadmium and mercury .
4. TPPO CAS 791-28-6 functions as a weak Lewis base organocatalyst for the selective reduction of conjugated polyunsaturated ketones, and can be reduced back to triphenylphosphine for recycling .

1. Store Triphenylphosphine oxide CAS 791-28-6 at room temperature, recommended in a cool and dark place below 15°C .
2. TPPO CAS 791-28-6 should be kept in a tightly closed container and stored away from strong oxidizing agents and strong acids .
3. For long-term storage, Triphenylphosphine oxide CAS 791-28-6 powder can be kept at -20°C for up to 3 years or at 4°C for up to 2 years .
4. Stock solutions of Triphenylphosphine oxide CAS 791-28-6 should be stored at -80°C for up to 6 months or at -20°C for up to 1 month, avoiding repeated freeze-thaw cycles .

1. Triphenylphosphine oxide CAS 791-28-6 is harmful if swallowed (H302), with an oral LD50 of 685 mg/kg in rats .
2. TPPO CAS 791-28-6 causes skin irritation (Category 2) and serious eye irritation .
3. Triphenylphosphine oxide CAS 791-28-6 may cause respiratory irritation (STOT Single Exposure Category 3), and may cause damage to the central nervous system and liver through prolonged or repeated exposure .
4. TPPO CAS 791-28-6 is harmful to aquatic life with long-lasting effects (H411/H412), with a fish LC50 of 50.8-56.7 mg/L .

1. Triphenylphosphine oxide CAS 791-28-6 is not safe for ingestion and should be handled only by trained personnel with appropriate personal protective equipment .
2. TPPO CAS 791-28-6 is classified as a warning-level hazard with the signal word Warning under GHS .
3. Triphenylphosphine oxide CAS 791-28-6 requires protective gloves, safety goggles, and appropriate clothing in a well-ventilated area to avoid dust inhalation and skin contact .
4. TPPO CAS 791-28-6 must not be released into drains or the environment, and spills should be swept up and placed in closed containers for disposal as hazardous waste .

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