What's 1-Bromobutane CAS 109-65-9 Used For?

Oct 19, 2026

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Main industrial uses

The first use is alkylation in organic synthesis. 1-Bromobutane transfers an n-butyl group to nitrogen, oxygen, sulfur, or carbon nucleophiles. Process chemists specify CAS 109-65-9 when they need a primary bromide with a short, linear chain rather than a branched butyl halide, because the isomer mix changes both rate and impurity profile.

The second use is organometallic chemistry. 1-Bromobutane is a standard precursor for n-butyllithium and for n-butyl Grignard reagents. Incoming quality-water, residual acid, and related bromides-matters here, because moisture and extra acidity can kill initiation or raise Wurtz coupling.

The third use is downstream manufacturing. 1-Bromobutane appears in routes to local anesthetics such as procaine and tetracaine, and in selected dye and fragrance intermediates. It is also used to make pesticides and quaternary ammonium salts, and in some plants as a cleaning or degreasing solvent. It remains a chemical intermediate, not a finished drug or perfume oil.

 

1-Bromobutane CAS 109-65-9

 

Typical specification buyers ask for

A practical datasheet for 1-bromobutane CAS 109-65-9 includes appearance (colorless transparent liquid), molecular formula C4H9Br, EINECS 203-691-9, melting point about −112°C, boiling point 100–104°C, density about 1.276 g/mL, and assay ≥99%. Packing is commonly 1 L bottles, 25 L drums, 200 L drums, or 1000 L IBC, or as agreed. Under proper sealed storage, shelf life is typically 24 months.

Storage and handling notes for purchasers

1-Bromobutane is a highly flammable liquid and vapor, with a flash point around 18–23°C. Store it in a cool, dry, well-ventilated place, protected from light, with the container tightly closed. Keep it away from heat, sparks, open flames, and hot surfaces. Ground containers and control static during transfer. The vapor is harmful if inhaled and can irritate skin and eyes; some classifications also flag carcinogenicity and reproductive toxicity concerns, so uncontrolled handling is not acceptable. Use gloves, protective clothing, and eye/face protection in a fume hood or well-ventilated area. Do not release spills to drains; absorb with inert material and dispose of as hazardous waste. Store locked, accessible only to trained personnel.

 

Why buyers source from Arise New Material

As a Shanghai-based supplier of organic chemicals, Arise New Material supports sample trials and commercial lots, with flexible MOQ (often from 1 kg, depending on the item). Documents such as COA, MSDS, commercial invoice, and packing list can be prepared for customs. Lead time is typically 6–10 days by courier or air, or longer by sea depending on destination.

If you are comparing n-butyl bromides for alkylation, Grignard/lithium chemistry, or quaternary salt production, review 1-bromobutane CAS 109-65-9 against your process water limit and isomer requirement. Contact Shanghai Arise New Material Co., Ltd. for COA, packing options, and a quotation. Tell us whether the job is organometallic, pharmaceutical intermediate, or surfactant/quat synthesis so we can match grade and packing to your plant.

 

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1-Bromobutane CAS 109-65-9

 

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